Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM256294'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256294 (US9487488, 18) Show SMILES FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)nc1 Show InChI InChI=1S/C26H20F3N7O2S/c27-26(28,29)19-9-10-20(30-14-19)15-36(25-23(16-5-6-16)22-4-2-1-3-18(22)13-31-25)39(37,38)21-11-7-17(8-12-21)24-32-34-35-33-24/h1-4,7-14,16H,5-6,15H2,(H,32,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair