Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM256301'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256301 (US9487488, 25) Show SMILES Cc1n[nH]c(n1)-c1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)C(F)(F)F)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N6O2S/c1-17-34-26(36-35-17)19-8-12-23(13-9-19)40(38,39)37(16-22-11-10-21(15-32-22)28(29,30)31)27-25(18-6-7-18)24-5-3-2-4-20(24)14-33-27/h2-5,8-15,18H,6-7,16H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
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