Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM256302'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256302 (US9487488, 26) Show SMILES Cc1cc(ccc1-c1ncn[nH]1)S(=O)(=O)N(Cc1ccc(cn1)C(F)(F)F)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N6O2S/c1-17-12-22(10-11-23(17)26-34-16-35-36-26)40(38,39)37(15-21-9-8-20(14-32-21)28(29,30)31)27-25(18-6-7-18)24-5-3-2-4-19(24)13-33-27/h2-5,8-14,16,18H,6-7,15H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair