Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM256304'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256304 (US9487488, 28) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(nc2)-c2ncn[nH]2)cc1 Show InChI InChI=1S/C25H16F6N6O3S/c26-24(27,28)21-19-4-2-1-3-16(19)11-33-23(21)37(13-15-5-7-17(8-6-15)40-25(29,30)31)41(38,39)18-9-10-20(32-12-18)22-34-14-35-36-22/h1-12,14H,13H2,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
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