Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM256311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256311 (US9487488, 35) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cn2)-c2noc(=O)[nH]2)cc1 Show InChI InChI=1S/C27H20F3N5O5S/c28-27(29,30)39-20-10-5-16(6-11-20)15-35(25-23(17-7-8-17)21-4-2-1-3-18(21)13-32-25)41(37,38)22-12-9-19(14-31-22)24-33-26(36)40-34-24/h1-6,9-14,17H,7-8,15H2,(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
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