Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50036524'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50036524 (CHEMBL3353570) Show SMILES OC(=O)c1ccccc1S(=O)(=O)N(Cc1ccccc1)c1ncc(cc1Cl)C(F)(F)F Show InChI InChI=1S/C20H14ClF3N2O4S/c21-16-10-14(20(22,23)24)11-25-18(16)26(12-13-6-2-1-3-7-13)31(29,30)17-9-5-4-8-15(17)19(27)28/h1-11H,12H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
RaQualia Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx				Bioorg Med Chem Lett 24: 5364-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.074 BindingDB Entry DOI: 10.7270/Q2TB18HX
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