Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50036549'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50036549 (CHEMBL3353605) Show SMILES CCn1ncc2cc(CN(c3ncc(cc3Cl)C(F)(F)F)S(=O)(=O)c3ccc(cc3)C(O)=O)ccc12 Show InChI InChI=1S/C23H18ClF3N4O4S/c1-2-30-20-8-3-14(9-16(20)11-29-30)13-31(21-19(24)10-17(12-28-21)23(25,26)27)36(34,35)18-6-4-15(5-7-18)22(32)33/h3-12H,2,13H2,1H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
RaQualia Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx				Bioorg Med Chem Lett 24: 5364-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.074 BindingDB Entry DOI: 10.7270/Q2TB18HX
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