BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50317569'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50317569 (3-Chlorophenyl-(1R,2S,5R)-2-isopropyl-5-methylcycl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevation				Bioorg Med Chem Lett 20: 2729-32 (2010) Article DOI: 10.1016/j.bmcl.2010.03.076 BindingDB Entry DOI: 10.7270/Q27M083N
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Rattus norvegicus (Rat))	BDBM50317569 (3-Chlorophenyl-(1R,2S,5R)-2-isopropyl-5-methylcycl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevation				Bioorg Med Chem Lett 20: 2729-32 (2010) Article DOI: 10.1016/j.bmcl.2010.03.076 BindingDB Entry DOI: 10.7270/Q27M083N
Sapienza Universit£ di Roma Curated by ChEMBL					More data for this Ligand-Target Pair