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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50442670'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))
BDBM50442670
PNG
(CHEMBL2442051)
Show SMILES NCCN(Cc1cccs1)C(=O)c1ccccc1OCc1ccccc1
Show InChI InChI=1S/C21H22N2O2S/c22-12-13-23(15-18-9-6-14-26-18)21(24)19-10-4-5-11-20(19)25-16-17-7-2-1-3-8-17/h1-11,14H,12-13,15-16,22H2
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.24E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assay


Bioorg Med Chem Lett 23: 6118-22 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.016
BindingDB Entry DOI: 10.7270/Q2125V4N
More data for this
Ligand-Target Pair