Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50463874'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50463874 (CHEMBL4239691) Show SMILES Cc1cccc(c1)[C@H](NC(=O)c1ccc2cccnc2c1)c1ncccc1C(F)(F)F |r| Show InChI InChI=1S/C24H18F3N3O/c1-15-5-2-6-17(13-15)21(22-19(24(25,26)27)8-4-12-29-22)30-23(31)18-10-9-16-7-3-11-28-20(16)14-18/h2-14,21H,1H3,(H,30,31)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...				J Med Chem 61: 8186-8201 (2018) Article DOI: 10.1021/acs.jmedchem.8b00518 BindingDB Entry DOI: 10.7270/Q2TH8QCW
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mus musculus)	BDBM50463874 (CHEMBL4239691) Show SMILES Cc1cccc(c1)[C@H](NC(=O)c1ccc2cccnc2c1)c1ncccc1C(F)(F)F |r| Show InChI InChI=1S/C24H18F3N3O/c1-15-5-2-6-17(13-15)21(22-19(24(25,26)27)8-4-12-29-22)30-23(31)18-10-9-16-7-3-11-28-20(16)14-18/h2-14,21H,1H3,(H,30,31)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...				J Med Chem 61: 8186-8201 (2018) Article DOI: 10.1021/acs.jmedchem.8b00518 BindingDB Entry DOI: 10.7270/Q2TH8QCW
					More data for this Ligand-Target Pair