Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50463876'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50463876 (CHEMBL4238921) Show SMILES COc1ccc(cn1)C(=O)N[C@@H](c1ccc(cc1)C(F)(F)F)c1ncccc1C(F)(F)F |r| Show InChI InChI=1S/C21H15F6N3O2/c1-32-16-9-6-13(11-29-16)19(31)30-17(12-4-7-14(8-5-12)20(22,23)24)18-15(21(25,26)27)3-2-10-28-18/h2-11,17H,1H3,(H,30,31)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...				J Med Chem 61: 8186-8201 (2018) Article DOI: 10.1021/acs.jmedchem.8b00518 BindingDB Entry DOI: 10.7270/Q2TH8QCW
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mus musculus)	BDBM50463876 (CHEMBL4238921) Show SMILES COc1ccc(cn1)C(=O)N[C@@H](c1ccc(cc1)C(F)(F)F)c1ncccc1C(F)(F)F |r| Show InChI InChI=1S/C21H15F6N3O2/c1-32-16-9-6-13(11-29-16)19(31)30-17(12-4-7-14(8-5-12)20(22,23)24)18-15(21(25,26)27)3-2-10-28-18/h2-11,17H,1H3,(H,30,31)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...				J Med Chem 61: 8186-8201 (2018) Article DOI: 10.1021/acs.jmedchem.8b00518 BindingDB Entry DOI: 10.7270/Q2TH8QCW
					More data for this Ligand-Target Pair