Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM127304'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM127304 (US8791268, 4) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Cc1cccc(F)c1)C(F)(F)F Show InChI InChI=1S/C21H23F4N3O/c1-14-7-9-28(10-8-14)20-16(5-6-18(27-20)21(23,24)25)13-26-19(29)12-15-3-2-4-17(22)11-15/h2-6,11,14H,7-10,12-13H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...				US Patent US8791268 (2014) BindingDB Entry DOI: 10.7270/Q2BV7F9D
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM127304 (US8791268, 4) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Cc1cccc(F)c1)C(F)(F)F Show InChI InChI=1S/C21H23F4N3O/c1-14-7-9-28(10-8-14)20-16(5-6-18(27-20)21(23,24)25)13-26-19(29)12-15-3-2-4-17(22)11-15/h2-6,11,14H,7-10,12-13H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced TRPV1 activation by FLIPR method				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128266 BindingDB Entry DOI: 10.7270/Q2CV4NG9
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM127304 (US8791268, 4) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Cc1cccc(F)c1)C(F)(F)F Show InChI InChI=1S/C21H23F4N3O/c1-14-7-9-28(10-8-14)20-16(5-6-18(27-20)21(23,24)25)13-26-19(29)12-15-3-2-4-17(22)11-15/h2-6,11,14H,7-10,12-13H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...				US Patent US8791268 (2014) BindingDB Entry DOI: 10.7270/Q2BV7F9D
					More data for this Ligand-Target Pair