Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50253964'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50253964 (5-(azetidin-1-yl)-N2-(2,6-dichlorophenyl)-N7-(4-(t...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCC2)cc1 Show InChI InChI=1S/C21H15Cl2F3N6S/c22-13-3-1-4-14(23)15(13)28-20-29-16-17(27-12-7-5-11(6-8-12)21(24,25)26)30-19(31-18(16)33-20)32-9-2-10-32/h1,3-8H,2,9-10H2,(H,28,29)(H,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50253964 (5-(azetidin-1-yl)-N2-(2,6-dichlorophenyl)-N7-(4-(t...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCC2)cc1 Show InChI InChI=1S/C21H15Cl2F3N6S/c22-13-3-1-4-14(23)15(13)28-20-29-16-17(27-12-7-5-11(6-8-12)21(24,25)26)30-19(31-18(16)33-20)32-9-2-10-32/h1,3-8H,2,9-10H2,(H,28,29)(H,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair