Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50332848'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50332848 (2-(4-cyclopropylpiperazin-1-yl)-N-(4-(trifluoromet...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3CCN(CCc23)c2ncccc2C(F)(F)F)N2CCN(CC2)C2CC2)cc1 Show InChI InChI=1S/C28H29F6N7/c29-27(30,31)18-3-5-19(6-4-18)36-24-21-9-12-40(25-22(28(32,33)34)2-1-11-35-25)13-10-23(21)37-26(38-24)41-16-14-39(15-17-41)20-7-8-20/h1-6,11,20H,7-10,12-17H2,(H,36,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ level by FLIPR assay				Bioorg Med Chem Lett 20: 7142-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.006 BindingDB Entry DOI: 10.7270/Q26Q1XH0
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50332848 (2-(4-cyclopropylpiperazin-1-yl)-N-(4-(trifluoromet...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3CCN(CCc23)c2ncccc2C(F)(F)F)N2CCN(CC2)C2CC2)cc1 Show InChI InChI=1S/C28H29F6N7/c29-27(30,31)18-3-5-19(6-4-18)36-24-21-9-12-40(25-22(28(32,33)34)2-1-11-35-25)13-10-23(21)37-26(38-24)41-16-14-39(15-17-41)20-7-8-20/h1-6,11,20H,7-10,12-17H2,(H,36,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ level by FLIPR assay				Bioorg Med Chem Lett 20: 7142-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.006 BindingDB Entry DOI: 10.7270/Q26Q1XH0
					More data for this Ligand-Target Pair