Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50434921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434921 (CHEMBL2385419) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(37.09,-35.97,;37.09,-37.51,;35.76,-38.29,;35.76,-39.83,;34.42,-37.52,;33.09,-38.29,;31.75,-37.52,;31.75,-35.97,;30.41,-35.21,;29.09,-35.98,;29.08,-37.52,;30.42,-38.29,;30.42,-39.83,;29.08,-40.6,;27.75,-39.82,;26.42,-40.58,;26.4,-42.12,;25.06,-42.88,;27.74,-42.91,;29.08,-42.14,;27.75,-35.21,;27.75,-33.67,;26.42,-35.98,;26.41,-34.44,;38.42,-38.28,;38.42,-39.82,;39.75,-40.59,;41.09,-39.82,;42.42,-40.58,;43.75,-39.81,;45.09,-40.58,;42.97,-38.47,;44.51,-38.47,;41.08,-38.27,;42.41,-37.49,;39.74,-37.51,)| Show InChI InChI=1S/C24H29F4N3O4S/c1-14-4-8-18(9-5-14)35-23-17(7-11-21(30-23)24(26,27)28)13-29-22(32)15(2)16-6-10-20(19(25)12-16)31-36(3,33)34/h6-7,10-12,14-15,18,31H,4-5,8-9,13H2,1-3H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434921 (CHEMBL2385419) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCC(C)CC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(37.09,-35.97,;37.09,-37.51,;35.76,-38.29,;35.76,-39.83,;34.42,-37.52,;33.09,-38.29,;31.75,-37.52,;31.75,-35.97,;30.41,-35.21,;29.09,-35.98,;29.08,-37.52,;30.42,-38.29,;30.42,-39.83,;29.08,-40.6,;27.75,-39.82,;26.42,-40.58,;26.4,-42.12,;25.06,-42.88,;27.74,-42.91,;29.08,-42.14,;27.75,-35.21,;27.75,-33.67,;26.42,-35.98,;26.41,-34.44,;38.42,-38.28,;38.42,-39.82,;39.75,-40.59,;41.09,-39.82,;42.42,-40.58,;43.75,-39.81,;45.09,-40.58,;42.97,-38.47,;44.51,-38.47,;41.08,-38.27,;42.41,-37.49,;39.74,-37.51,)| Show InChI InChI=1S/C24H29F4N3O4S/c1-14-4-8-18(9-5-14)35-23-17(7-11-21(30-23)24(26,27)28)13-29-22(32)15(2)16-6-10-20(19(25)12-16)31-36(3,33)34/h6-7,10-12,14-15,18,31H,4-5,8-9,13H2,1-3H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	6.0	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of pH 6 to 6.3-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair