Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50528808'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528808 (CHEMBL4476530) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F Show InChI InChI=1S/C31H37F4N5O3S/c1-39(2)30(19-22-7-5-4-6-8-22)13-15-40(16-14-30)28-18-25(31(33,34)35)11-10-24(28)21-37-29(41)36-20-23-9-12-27(26(32)17-23)38-44(3,42)43/h4-12,17-18,38H,13-16,19-21H2,1-3H3,(H2,36,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	266	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from recombinant human TRPV1 expressed in CHO cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634 BindingDB Entry DOI: 10.7270/Q2765JR7
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528808 (CHEMBL4476530) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F Show InChI InChI=1S/C31H37F4N5O3S/c1-39(2)30(19-22-7-5-4-6-8-22)13-15-40(16-14-30)28-18-25(31(33,34)35)11-10-24(28)21-37-29(41)36-20-23-9-12-27(26(32)17-23)38-44(3,42)43/h4-12,17-18,38H,13-16,19-21H2,1-3H3,(H2,36,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV1 expressed in CHO cells assessed as as inhibition of capsaicin-induced calcium uptake incubated for 5 m...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634 BindingDB Entry DOI: 10.7270/Q2765JR7
					More data for this Ligand-Target Pair