Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM230164'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230164 (US9340500, I-008) Show SMILES Cc1c(cc(-c2ccccc2)n1CCCN1CCCCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H30F3N3O/c1-20-24(26(34)31-23-13-8-12-22(18-23)27(28,29)30)19-25(21-10-4-2-5-11-21)33(20)17-9-16-32-14-6-3-7-15-32/h2,4-5,8,10-13,18-19H,3,6-7,9,14-17H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	327	-38.5	n/a	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230164 (US9340500, I-008) Show SMILES Cc1c(cc(-c2ccccc2)n1CCCN1CCCCC1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C27H30F3N3O/c1-20-24(26(34)31-23-13-8-12-22(18-23)27(28,29)30)19-25(21-10-4-2-5-11-21)33(20)17-9-16-32-14-6-3-7-15-32/h2,4-5,8,10-13,18-19H,3,6-7,9,14-17H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair