Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM230220'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230220 (US9340500, I-064) Show SMILES CN(CCCn1c(C)c(cc1-c1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F)C(=O)C(Cl)(Cl)Cl Show InChI InChI=1S/C25H23Cl3F3N3O2/c1-16-20(22(35)32-19-11-6-10-18(14-19)25(29,30)31)15-21(17-8-4-3-5-9-17)34(16)13-7-12-33(2)23(36)24(26,27)28/h3-6,8-11,14-15H,7,12-13H2,1-2H3,(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	713	-36.5	n/a	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
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