Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM230249'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230249 (US9340500, I-093) Show SMILES Cc1c(cc(n1CCC(=O)N1CCNCC1)C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H31F3N4O2/c1-16-19(22(33)29-18-7-5-6-17(14-18)24(25,26)27)15-20(23(2,3)4)31(16)11-8-21(32)30-12-9-28-10-13-30/h5-7,14-15,28H,8-13H2,1-4H3,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	530	-37.3	1.40E+3	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
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