BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM50117642'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117642 (CHEMBL3613632) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117642 (CHEMBL3613632) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair