Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane prolyl 4-hydroxylase' and Ligand = 'BDBM3644'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM3644 (US8524699, 55) Show SMILES CCN(CC)CCCCCCNc1cc(ncn1)-n1[nH]cc(-c2cccnc2)c1=O Show InChI InChI=1S/C22H31N7O/c1-3-28(4-2)13-8-6-5-7-12-24-20-14-21(26-17-25-20)29-22(30)19(16-27-29)18-10-9-11-23-15-18/h9-11,14-17,27H,3-8,12-13H2,1-2H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.5	25
Bayer Intellectual Property GmbH US Patent					Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.				US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4
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