Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (Rattus norvegicus) | BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity at norepinephrine transporter using [3H]nisoxetine as radioligand from rat brain | Bioorg Med Chem Lett 11: 3169-73 (2001) BindingDB Entry DOI: 10.7270/Q2CC117R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDA-IRP Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat brain norepinephrine transporter | J Med Chem 46: 2589-98 (2003) Article DOI: 10.1021/jm030008u BindingDB Entry DOI: 10.7270/Q2H70GJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 2.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description The compound was tested for binding affinity nisoxatine ligand | J Med Chem 42: 4446-55 (1999) BindingDB Entry DOI: 10.7270/Q2NS0VMV | |||||||||||
More data for this Ligand-Target Pair |