Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transthyretin' and Ligand = 'BDBM50301376'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Homo sapiens (Human))	BDBM50301376 ((E/Z)-3-(4-iodophenylimino)-5-nitroindolin-2-one |...) Show SMILES [O-][N+](=O)c1ccc2NC(=O)\C(=N/c3ccc(I)cc3)c2c1 Show InChI InChI=1S/C14H8IN3O3/c15-8-1-3-9(4-2-8)16-13-11-7-10(18(20)21)5-6-12(11)17-14(13)19/h1-7H,(H,16,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assay				Bioorg Med Chem Lett 19: 5270-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.004 BindingDB Entry DOI: 10.7270/Q2SF2W7W
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