Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM357744'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM357744 (KM-05-80/(I-1) | US10214530, Example 1) Show SMILES O=c1[nH]c(=O)c2n(Cc3ccccc3)c(Cc3nc4ccccc4[nH]3)nc2n1C1CC1 Show InChI InChI=1S/C23H20N6O2/c30-22-20-21(29(15-10-11-15)23(31)27-22)26-19(28(20)13-14-6-2-1-3-7-14)12-18-24-16-8-4-5-9-17(16)25-18/h1-9,15H,10-13H2,(H,24,25)(H,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00598 BindingDB Entry DOI: 10.7270/Q2G164VF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM357744 (KM-05-80/(I-1) | US10214530, Example 1) Show SMILES O=c1[nH]c(=O)c2n(Cc3ccccc3)c(Cc3nc4ccccc4[nH]3)nc2n1C1CC1 Show InChI InChI=1S/C23H20N6O2/c30-22-20-21(29(15-10-11-15)23(31)27-22)26-19(28(20)13-14-6-2-1-3-7-14)12-18-24-16-8-4-5-9-17(16)25-18/h1-9,15H,10-13H2,(H,24,25)(H,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN US Patent					Assay Description These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...				US Patent US10214530 (2019) BindingDB Entry DOI: 10.7270/Q25B04SK
					More data for this Ligand-Target Pair				3D Structure (crystal)