Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50145642'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50145642 (CHEMBL3764344) Show SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)N1CCC2(CCNC(C2)C(O)=O)CC1)C(F)(F)F |r| Show InChI InChI=1S/C26H29ClF3N7O3/c1-15-4-9-37(35-15)19-12-16(27)2-3-17(19)22(26(28,29)30)40-21-13-20(33-24(31)34-21)36-10-6-25(7-11-36)5-8-32-18(14-25)23(38)39/h2-4,9,12-13,18,22,32H,5-8,10-11,14H2,1H3,(H,38,39)(H2,31,33,34)/t18?,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	949	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 26: 1124-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.064 BindingDB Entry DOI: 10.7270/Q2WD42DJ
					More data for this Ligand-Target Pair