Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50145647'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50145647 (CHEMBL3764524) Show SMILES CN1CC2(C[C@H]1C(O)=O)CCN(CC2)c1cc(O[C@H](c2ccc(Cl)cc2-n2ccc(C)n2)C(F)(F)F)nc(N)n1 |r| Show InChI InChI=1S/C26H29ClF3N7O3/c1-15-5-8-37(34-15)18-11-16(27)3-4-17(18)22(26(28,29)30)40-21-12-20(32-24(31)33-21)36-9-6-25(7-10-36)13-19(23(38)39)35(2)14-25/h3-5,8,11-12,19,22H,6-7,9-10,13-14H2,1-2H3,(H,38,39)(H2,31,32,33)/t19-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	871	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 26: 1124-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.064 BindingDB Entry DOI: 10.7270/Q2WD42DJ
					More data for this Ligand-Target Pair