Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50145650'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50145650 (CHEMBL3765094) Show SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1ccnc(c1)N1CCC2(CNC(C2)C(O)=O)CC1)C(F)(F)F |r| Show InChI InChI=1S/C26H27ClF3N5O3/c1-16-5-9-35(33-16)21-12-17(27)2-3-19(21)23(26(28,29)30)38-18-4-8-31-22(13-18)34-10-6-25(7-11-34)14-20(24(36)37)32-15-25/h2-5,8-9,12-13,20,23,32H,6-7,10-11,14-15H2,1H3,(H,36,37)/t20?,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 26: 1124-9 (2016) Article DOI: 10.1016/j.bmcl.2016.01.064 BindingDB Entry DOI: 10.7270/Q2WD42DJ
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