Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 2' and Ligand = 'BDBM445672'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human))	BDBM445672 (Ex. 10/KM-06-90/(I-10) | US10683309, Example 10 | ...) Show SMILES CCn1c2nc(Cc3cn4ccccc4n3)n(Cc3ccc(cc3)-c3nccs3)c2c(=O)[nH]c1=O Show InChI InChI=1S/C25H21N7O2S/c1-2-31-22-21(23(33)29-25(31)34)32(14-16-6-8-17(9-7-16)24-26-10-12-35-24)20(28-22)13-18-15-30-11-4-3-5-19(30)27-18/h3-12,15H,2,13-14H2,1H3,(H,29,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent					Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...				US Patent US11028104 (2021) BindingDB Entry DOI: 10.7270/Q2JM2DRC
					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human))	BDBM445672 (Ex. 10/KM-06-90/(I-10) | US10683309, Example 10 | ...) Show SMILES CCn1c2nc(Cc3cn4ccccc4n3)n(Cc3ccc(cc3)-c3nccs3)c2c(=O)[nH]c1=O Show InChI InChI=1S/C25H21N7O2S/c1-2-31-22-21(23(33)29-25(31)34)32(14-16-6-8-17(9-7-16)24-26-10-12-35-24)20(28-22)13-18-15-30-11-4-3-5-19(30)27-18/h3-12,15H,2,13-14H2,1H3,(H,29,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent					Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...				US Patent US10683309 (2020) BindingDB Entry DOI: 10.7270/Q2NG4TQ6
					More data for this Ligand-Target Pair