Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 2' and Ligand = 'BDBM445692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human))	BDBM445692 (Ex. 28/KM-06-148/(I-28) | US10683309, Example 28 |...) Show SMILES CCn1c2nc(Cc3cn4cc(Cl)sc4n3)n(Cc3ccc(NC(C)=O)cc3)c2c(=O)[nH]c1=O Show InChI InChI=1S/C22H20ClN7O3S/c1-3-29-19-18(20(32)27-21(29)33)30(9-13-4-6-14(7-5-13)24-12(2)31)17(26-19)8-15-10-28-11-16(23)34-22(28)25-15/h4-7,10-11H,3,8-9H2,1-2H3,(H,24,31)(H,27,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent					Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...				US Patent US11028104 (2021) BindingDB Entry DOI: 10.7270/Q2JM2DRC
					More data for this Ligand-Target Pair
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human))	BDBM445692 (Ex. 28/KM-06-148/(I-28) | US10683309, Example 28 |...) Show SMILES CCn1c2nc(Cc3cn4cc(Cl)sc4n3)n(Cc3ccc(NC(C)=O)cc3)c2c(=O)[nH]c1=O Show InChI InChI=1S/C22H20ClN7O3S/c1-3-29-19-18(20(32)27-21(29)33)30(9-13-4-6-14(7-5-13)24-12(2)31)17(26-19)8-15-10-28-11-16(23)34-22(28)25-15/h4-7,10-11H,3,8-9H2,1-2H3,(H,24,31)(H,27,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V. US Patent					Assay Description The full-length coding sequences of human TPH1 and TPH2 were PCR amplified, ligated into a MBP fusion vector (pMalc2x, New England Biolabs, MA, USA) ...				US Patent US10683309 (2020) BindingDB Entry DOI: 10.7270/Q2NG4TQ6
					More data for this Ligand-Target Pair