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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043452'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043452
PNG
(CHEMBL337663 | {Allyl-[4-(2-ethyl-5,7-dimethyl-imi...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC=C)C(C(O)=O)c1cc(F)ccc1F
Show InChI InChI=1S/C28H28F2N4O2/c1-5-13-33(26(28(35)36)22-15-20(29)9-12-23(22)30)21-10-7-19(8-11-21)16-34-24(6-2)32-25-17(3)14-18(4)31-27(25)34/h5,7-12,14-15,26H,1,6,13,16H2,2-4H3,(H,35,36)
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PC cid
PC sid
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Similars
PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair