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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043454'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043454
PNG
(CHEMBL134491 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...)
Show SMILES CCN(C(C(O)=O)c1cccc(C)c1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Show InChI InChI=1S/C28H32N4O2/c1-6-24-30-25-19(4)16-20(5)29-27(25)32(24)17-21-11-13-23(14-12-21)31(7-2)26(28(33)34)22-10-8-9-18(3)15-22/h8-16,26H,6-7,17H2,1-5H3,(H,33,34)
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 66n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair