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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043466'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043466
PNG
(CHEMBL424643 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(C)C(C(O)=O)c2ccccc2)c(C)c1
Show InChI InChI=1S/C27H30N4O2/c1-6-23-29-24-18(3)14-19(4)28-26(24)31(23)16-20-12-13-22(17(2)15-20)30(5)25(27(32)33)21-10-8-7-9-11-21/h7-15,25H,6,16H2,1-5H3,(H,32,33)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 70n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair