BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043467'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043467
PNG
(CHEMBL136028 | {[4-(2-Ethyl-5,7-dimethyl-imidazo[4...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(CC(C)C)C(C(O)=O)c1ccccc1
Show InChI InChI=1S/C29H34N4O2/c1-6-25-31-26-20(4)16-21(5)30-28(26)33(25)18-22-12-14-24(15-13-22)32(17-19(2)3)27(29(34)35)23-10-8-7-9-11-23/h7-16,19,27H,6,17-18H2,1-5H3,(H,34,35)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 22n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair