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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043468'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043468
PNG
((2,5-Difluoro-phenyl)-{ethyl-[4-(2-ethyl-5,7-dimet...)
Show SMILES CCN(C(C(O)=O)c1cc(F)ccc1F)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Show InChI InChI=1S/C27H28F2N4O2/c1-5-23-31-24-16(3)13-17(4)30-26(24)33(23)15-18-7-10-20(11-8-18)32(6-2)25(27(34)35)21-14-19(28)9-12-22(21)29/h7-14,25H,5-6,15H2,1-4H3,(H,34,35)
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 88n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair