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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043472'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043472
PNG
(CHEMBL335514 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)cc1
Show InChI InChI=1S/C25H26N4O2/c1-4-21-28-22-16(2)14-17(3)26-24(22)29(21)15-18-10-12-20(13-11-18)27-23(25(30)31)19-8-6-5-7-9-19/h5-14,23,27H,4,15H2,1-3H3,(H,30,31)
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PC sid
UniChem

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PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair