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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50043477'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(RABBIT)		BDBM50043477
PNG
(CHEMBL135704 | [4-(2-Ethyl-5,7-dimethyl-imidazo[4,...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(NC(C(O)=O)c2ccccc2)c(C)c1
Show InChI InChI=1S/C26H28N4O2/c1-5-22-29-23-17(3)13-18(4)27-25(23)30(22)15-19-11-12-21(16(2)14-19)28-24(26(31)32)20-9-7-6-8-10-20/h6-14,24,28H,5,15H2,1-4H3,(H,31,32)
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 100n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair