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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50467140'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(Homo sapiens (Human))		BDBM50467140
PNG
(CHEMBL4289788)
Show SMILES CCCCc1nc(C)c(CC(=S)N(C)C)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1
Show InChI InChI=1S/C28H31N5O3S/c1-5-6-11-24-29-18(2)23(16-25(37)32(3)4)27(34)33(24)17-19-12-14-20(15-13-19)21-9-7-8-10-22(21)26-30-28(35)36-31-26/h7-10,12-15H,5-6,11,16-17H2,1-4H3,(H,30,31,35)
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n/an/a 1.60n/an/an/an/an/an/a



Boryung Pharmaceuticals Co. Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at type-1 angiotensin 2 receptor (unknown origin) by calcium mobilizing assay

Bioorg Med Chem Lett 28: 3155-3160 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.036
BindingDB Entry DOI: 10.7270/Q2X63QMZ
More data for this
Ligand-Target Pair