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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50503899'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(Homo sapiens (Human))		BDBM50503899
PNG
(CHEMBL4471668)
Show SMILES CCCCc1nc(Cl)c(CNC(=O)C(CS)Cc2ccc3ccccc3c2)n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C36H36ClN3O3S/c1-2-3-12-33-39-34(37)32(21-38-35(41)29(23-44)20-25-15-16-26-8-4-5-9-28(26)19-25)40(33)22-24-13-17-27(18-14-24)30-10-6-7-11-31(30)36(42)43/h4-11,13-19,29,44H,2-3,12,20-23H2,1H3,(H,38,41)(H,42,43)
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 158n/an/an/an/an/an/an/an/a



Theravance Biopharma US Inc.

Curated by ChEMBL


Assay Description
Displacement of Europium-labeled angiotensin-2 from human AT1 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIA

ACS Med Chem Lett 10: 86-91 (2019)


Article DOI: 10.1021/acsmedchemlett.8b00462
BindingDB Entry DOI: 10.7270/Q2D50R6V
More data for this
Ligand-Target Pair