BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor' and Ligand = 'BDBM82258'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Ltd. Curated by ChEMBL					Assay Description Tested for in vitro binding affinity against angiotensin II receptor of rat liver				J Med Chem 37: 3108-20 (1994) Article DOI: 10.1021/jm00045a016 BindingDB Entry DOI: 10.7270/Q21R6T7V
Glaxo Research and Development Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Displacement of [3H]-AII from the Angiotensin II receptor isolated from the liver of rats				J Med Chem 38: 4670-8 (1995) Article DOI: 10.1021/jm00023a006 BindingDB Entry DOI: 10.7270/Q21J9DHJ
Burroughs Wellcome Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of Angiotensin II receptor binding of radiolabeled AII to rat adrenal glomerulosa tissue by 50%				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z03B9M
TBA					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
E. I. du Pont de Nemours& Company, Inc. Curated by ChEMBL					Assay Description Inhibition of radioligand [3H]angiotensin II binding to angiotensin II receptor of rat adrenal cortical membrane				J Med Chem 34: 2525-47 (1991) BindingDB Entry DOI: 10.7270/Q2QN690P
E. I. du Pont de Nemours& Company, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM82258 (CAS_114798-26-4 \| Losartan \| NSC_3961) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested in vitro for inhibition of [125I]AII to rat uterine membranes				Citation and Details Article DOI: 10.1016/S0960-894X(01)81129-X BindingDB Entry DOI: 10.7270/Q2PN98BK
TBA					More data for this Ligand-Target Pair