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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-2 angiotensin II receptor' and Ligand = 'BDBM50043457'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-2 angiotensin II receptor


(RAT)		BDBM50043457
PNG
(CHEMBL135346 | {Ethyl-[4-(2-ethyl-5,7-dimethyl-imi...)
Show SMILES CCN(C(C(O)=O)c1ccccc1)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Show InChI InChI=1S/C27H30N4O2/c1-5-23-29-24-18(3)16-19(4)28-26(24)31(23)17-20-12-14-22(15-13-20)30(6-2)25(27(32)33)21-10-8-7-9-11-21/h7-16,25H,5-6,17H2,1-4H3,(H,32,33)
PDB

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PC cid
PC sid
UniChem

Patents

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PubMed
n/an/a 740n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair