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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-2 angiotensin II receptor' and Ligand = 'BDBM50043471'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-2 angiotensin II receptor


(RAT)		BDBM50043471
PNG
((2,5-Difluoro-phenyl)-{[4-(2-ethyl-5,7-dimethyl-im...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1cc(F)ccc1F
Show InChI InChI=1S/C26H26F2N4O2/c1-5-22-30-23-15(2)12-16(3)29-25(23)32(22)14-17-6-9-19(10-7-17)31(4)24(26(33)34)20-13-18(27)8-11-21(20)28/h6-13,24H,5,14H2,1-4H3,(H,33,34)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair