Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1' and Ligand = 'BDBM481119'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM481119 (US10906896, Cpd 207) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cncc(c3)C3=NN=C(C3)C(=O)Nc3cc(C)no3)c2)CC1 |c:39,t:37| Show InChI InChI=1S/C37H37N11O3/c1-23-4-9-29(40-35(49)26-7-5-25(6-8-26)22-48-14-12-47(3)13-15-48)18-31(23)42-37-39-11-10-30(41-37)27-17-28(21-38-20-27)32-19-33(45-44-32)36(50)43-34-16-24(2)46-51-34/h4-11,16-18,20-21H,12-15,19,22H2,1-3H3,(H,40,49)(H,43,50)(H,39,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.2	n/a	n/a	n/a	n/a	n/a	n/a
Inhibikase Therapeutics, Inc. US Patent					Assay Description Kinase base buffer (50 mM HEPES, pH 7.5 0.0015% Brij-35; 10 mM MgCl2 2 mM DTT) and Stop buffer, (100 mM HEPES, pH 7.5 0.015% Brij-35; 0.2% Coating Re...				US Patent US10906896 (2021) BindingDB Entry DOI: 10.7270/Q2G44TCQ
					More data for this Ligand-Target Pair