Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ABL1 [64-515]' and Ligand = 'BDBM477798'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human))	BDBM477798 (US10889571, Example 144 | US20240101536, Example 1...) Show SMILES C[C@@H]1COCc2nc3cc(cc(-c4cnsc4)c3n12)C(=O)Nc1ccc(OC(F)(F)Cl)cc1 |r| Show InChI InChI=1S/C22H17ClF2N4O3S/c1-12-9-31-10-19-28-18-7-13(6-17(20(18)29(12)19)14-8-26-33-11-14)21(30)27-15-2-4-16(5-3-15)32-22(23,24)25/h2-8,11-12H,9-10H2,1H3,(H,27,30)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [64-515] (Homo sapiens (Human))	BDBM477798 (US10889571, Example 144 | US20240101536, Example 1...) Show SMILES C[C@@H]1COCc2nc3cc(cc(-c4cnsc4)c3n12)C(=O)Nc1ccc(OC(F)(F)Cl)cc1 |r| Show InChI InChI=1S/C22H17ClF2N4O3S/c1-12-9-31-10-19-28-18-7-13(6-17(20(18)29(12)19)14-8-26-33-11-14)21(30)27-15-2-4-16(5-3-15)32-22(23,24)25/h2-8,11-12H,9-10H2,1H3,(H,27,30)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Terns, Inc. US Patent					Assay Description ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...				US Patent US10889571 (2021) BindingDB Entry DOI: 10.7270/Q27S7RW4
					More data for this Ligand-Target Pair