Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM249990'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM249990 (US9447106, 116 | US9556188, Compound 116) Show SMILES NC(=O)c1c2NC[C@@H]3CN(C[C@@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C |r| Show InChI InChI=1S/C24H23N5O3/c1-2-20(30)28-13-16-12-26-24-21(23(25)31)22(27-29(24)19(16)14-28)15-8-10-18(11-9-15)32-17-6-4-3-5-7-17/h2-11,16,19,26H,1,12-14H2,(H2,25,31)/t16-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
BeiGene, Ltd. US Patent					Assay Description Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...				US Patent US9556188 (2017) BindingDB Entry DOI: 10.7270/Q26Q2082
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM249990 (US9447106, 116 | US9556188, Compound 116) Show SMILES NC(=O)c1c2NC[C@@H]3CN(C[C@@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C |r| Show InChI InChI=1S/C24H23N5O3/c1-2-20(30)28-13-16-12-26-24-21(23(25)31)22(27-29(24)19(16)14-28)15-8-10-18(11-9-15)32-17-6-4-3-5-7-17/h2-11,16,19,26H,1,12-14H2,(H2,25,31)/t16-,19+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
BeiGene, Ltd. US Patent					Assay Description Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...				US Patent US9447106 (2016) BindingDB Entry DOI: 10.7270/Q21Z439C
					More data for this Ligand-Target Pair