Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM264130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM264130 (3-(3-Bromo-2-methylphenyl)-8-fluoro-1-methyl(d3)qu...) Show SMILES Cc1c(Br)cccc1-n1c(=O)n(C)c2c(F)cccc2c1=O |(-.91,3.78,;-2,2.69,;-3.33,3.47,;-3.33,5,;-4.67,2.69,;-4.67,1.15,;-3.33,.38,;-2,1.15,;-.67,.39,;-.67,-1.15,;-2,-1.93,;.67,-1.92,;.67,-3.46,;2,-1.15,;3.33,-1.93,;3.33,-3.47,;4.67,-1.15,;4.67,.38,;3.33,1.15,;2,.39,;.67,1.16,;.67,2.69,)| Show InChI InChI=1S/C16H12BrFN2O2/c1-9-11(17)6-4-8-13(9)20-15(21)10-5-3-7-12(18)14(10)19(2)16(20)22/h3-8H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, INVITROGEN Corporation), fluoresceinated peptide (1.5 μM), A...				US Patent US9714234 (2017) BindingDB Entry DOI: 10.7270/Q2474CW0
					More data for this Ligand-Target Pair