Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM264157'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM264157 (US9714234, 32) Show SMILES COCc1ccc2c(c1)[nH]c1c(ccc(-c3cccc(c3C)-n3c(=O)cc4c(F)cccn4c3=O)c21)C(N)=O |(-8.96,1.8,;-7.48,2.2,;-6.39,1.11,;-4.9,1.51,;-3.99,.27,;-2.46,.43,;-1.84,1.83,;-2.74,3.08,;-4.27,2.92,;-1.84,4.33,;-.37,3.85,;.96,4.62,;2.3,3.85,;2.3,2.31,;.96,1.54,;.96,,;-.37,-.77,;-.37,-2.31,;.96,-3.08,;2.3,-2.31,;2.3,-.77,;3.63,,;3.63,-3.08,;3.63,-4.62,;2.3,-5.39,;4.96,-5.39,;6.3,-4.62,;7.63,-5.39,;7.63,-6.93,;8.96,-4.62,;8.96,-3.08,;7.63,-2.31,;6.3,-3.08,;4.96,-2.31,;4.96,-.77,;-.37,2.31,;.96,6.16,;2.3,6.93,;-.37,6.93,)| Show InChI InChI=1S/C30H23FN4O4/c1-16-18(5-3-7-24(16)35-26(36)14-25-22(31)6-4-12-34(25)30(35)38)19-10-11-21(29(32)37)28-27(19)20-9-8-17(15-39-2)13-23(20)33-28/h3-14,33H,15H2,1-2H3,(H2,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, INVITROGEN Corporation), fluoresceinated peptide (1.5 μM), A...				US Patent US9714234 (2017) BindingDB Entry DOI: 10.7270/Q2474CW0
					More data for this Ligand-Target Pair