Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM267831'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM267831 (4-{8-amino-5-chloro-3-[(3R)-1-formylpiperidin-3-yl...) Show SMILES COc1ccnc(NC(=O)c2ccc(cc2)-c2nc([C@@H]3CCCN(C3)C(=O)C3(C)COC3)n3c(Cl)cnc(N)c23)c1 |r| Show InChI InChI=1S/C29H30ClN7O4/c1-29(15-41-16-29)28(39)36-11-3-4-19(14-36)26-35-23(24-25(31)33-13-21(30)37(24)26)17-5-7-18(8-6-17)27(38)34-22-12-20(40-2)9-10-32-22/h5-10,12-13,19H,3-4,11,14-16H2,1-2H3,(H2,31,33)(H,32,34,38)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V. US Patent					Assay Description BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...				US Patent US9718828 (2017) BindingDB Entry DOI: 10.7270/Q2H9977T
					More data for this Ligand-Target Pair