Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM378841'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM378841 (US10266528, Compound 16) Show SMILES Cc1cc(c(F)cc1CNC(=O)c1nc(no1)C(C)(C)C)-c1ccnc2[nH]c(=O)[nH]c12 Show InChI InChI=1S/C21H21FN6O3/c1-10-7-13(12-5-6-23-16-15(12)25-20(30)26-16)14(22)8-11(10)9-24-17(29)18-27-19(28-31-18)21(2,3)4/h5-8H,9H2,1-4H3,(H,24,29)(H2,23,25,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Briefly, 2.5× stocks of full-length human BTK (08-080) from CarnaBio USA, Inc., Natick, Mass., 1.6×ATP and appropriate kinKDR peptide substrate (FITC...				Bioorg Med Chem Lett 17: 5630-3 (2007) BindingDB Entry DOI: 10.7270/Q28S4S6R
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