Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM416714'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM416714 ((R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phen...) Show SMILES CCc1c(C#N)c(cn1[C@@H]1CCCN(C1)C(=O)OC(C)(C)C)-c1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C29H33N3O3/c1-5-27-25(18-30)26(21-13-15-24(16-14-21)34-23-11-7-6-8-12-23)20-32(27)22-10-9-17-31(19-22)28(33)35-29(2,3)4/h6-8,11-16,20,22H,5,9-10,17,19H2,1-4H3/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
JIANGSU HENGRUI MEDICINE CO., LTD. US Patent					Assay Description The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...				US Patent US10323037 (2019) BindingDB Entry DOI: 10.7270/Q2W098BW
					More data for this Ligand-Target Pair