Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM125911 (US8765727, 14) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | 7.8 | 25 |
Incyte Corporation US Patent | Assay Description One or more compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., A... | US Patent US8765727 (2014) BindingDB Entry DOI: 10.7270/Q2FQ9V87 | |||||||||||
More data for this Ligand-Target Pair |